| Identification | Back Directory | [Name]
DL-NORPHENYLEPHRINE HYDROCHLORIDE | [CAS]
4779-94-6 | [Synonyms]
WV 569
Vingsal
Coritat
Energona
Esbuphon
Stagural
Tonolift
Molycor R
NSC 100733
NSC 297582
norfenefrin
Depot-Novadral
TIMTEC-BB SBB000279
m-octopaminehydrochloride
nofenefrine hydrochloride
norphenephrinehydrochloride
dl-Norfenefrine hydrochloride
NORPHENYLEPHRINE HYDROCHLORIDE
(+/-)-NORPHENYLEPHRINE HYDROCHLORIDE
α-(AMinoMethyl)-3-hydroxybenzeneMethanol
M-HYDROXYPHENYLAMINOETHANOL HYDROCHLORIDE
(+/-)-NORPHENYLEPHRINE HYDROCHLORIDE, 98 %
3-(2-aMino-1-hydroxyethyl)phenol hydrochloride
Phenylephrine, Neosynephrine, Neophyrin, Mesaton
1-(m-Hydroxyphenyl)-2-aminoethanol hydrochloride
2-Amino-1-(3-hydroxyphenyl)ethanol hydrochloride
A-AMINOMETHYL-M-HYDROXYBENZYLALCOHOL HYDROCHLORIDE
α-aminomethyl-3-hydroxybenzyl alcohol hydrochloride
alpha-aminomethyl-3-hydroxy-benzylalcohohydrochloride
α-Aminomethyl-4-hydroxybenzyl alcohol hydrochloride
alpha-(aminomethyl)-3-hydroxy-benzenemethanohydrochloride
Phenylephrine Impurity A HCl (racemic Norphenylephrine HCl)
rac Norphenylephrine Hydrochloride
(Phenylephrine Impurity A)
Benzenemethanol, a-(aminomethyl)-3-hydroxy-, hydrochloride (9CI)
Benzyl alcohol, a-(aminomethyl)-m-hydroxy-, hydrochloride (6CI, 8CI) | [EINECS(EC#)]
225-323-6 | [Molecular Formula]
C8H12ClNO2 | [MDL Number]
MFCD00012879 | [MOL File]
4779-94-6.mol | [Molecular Weight]
189.64 |
| Chemical Properties | Back Directory | [Appearance]
white to almost white crystalline powder | [Melting point ]
162-164 °C(lit.)
| [storage temp. ]
-20°C Freezer, Under Inert Atmosphere | [solubility ]
DMSO (Slightly), Methanol (Slightly), Water (Slightly) | [form ]
Solid | [color ]
White to Off-White | [Merck ]
14,6699 |
| Hazard Information | Back Directory | [Chemical Properties]
white to almost white crystalline powder | [Uses]
Impurity A of phenylephrine. A phenylephrine derivative as leukotriene D4 antagonists. | [Originator]
Zordel,Grelan,Japan,1970 | [Definition]
ChEBI: Norfenefrine hydrochloride is a member of phenols. | [Manufacturing Process]
100 parts of the hydrochloride of meta-hydroxy-ω-aminoacetophenone of melting point 220°C to 222°C (obtainable by brominating metaacetoxyacetophenone, causing the bromoketone to react with sodium iodide, adding hexamethylenetetramine to the iodide in an indifferent solvent and scission of the addition product in acid solution) are shaken in aqueous solution with hydrogen in presence of 2 parts of palladium catalyst until 2 atomic proportions of hydrogen have been absorbed. The catalyst is now filtered and the filtrate evaporated in a vacuum; and the crystalline and completely dry residue is dissolved in absolute alcohol and a precipitate is produced by adding dry ether. The hydrochloride of metahydroxyphenylethanolamine thus obtained forms white crystals of melting point 159°C to 160°C.
| [Therapeutic Function]
Adrenergic |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
22 | [WGK Germany ]
3
| [RTECS ]
DN7400000
| [HS Code ]
2922504500 | [Toxicity]
LD50 oral in rat: 390mg/kg |
|
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