Identification | Back Directory | [Name]
8-isoprostaglandin A2 | [CAS]
474391-66-7 | [Synonyms]
8-isoprostaglandin A2 MYHXHCUNDDAEOZ-UKUWKSPLSA-N | [Molecular Formula]
C20H30O4 | [MDL Number]
MFCD12912353 | [MOL File]
474391-66-7.mol | [Molecular Weight]
334.45 |
Hazard Information | Back Directory | [Description]
Isoprostanes are prostaglandin (PG)-like compounds produced in vivo by free radical-catalyzed peroxidation of arachidonoyl-containing lipids. 8-iso PGA2 is one of several isoprostanes produced from peroxidation of arachidonic acid esterified in phospholipids. 8-iso PGA2 is the dehydration product of 8-iso PGE2, a potent renal vasoconstrictor. Evidence for the in vivo production of 8-iso PGA2 has been shown in rat liver under conditions of oxidative stress. There are no published studies of the pharmacological properties of 8-iso PGA2. | [Definition]
ChEBI: 8-iso Prostaglandin A2 is a prostanoid. |
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