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ChemicalBook--->CAS DataBase List--->473268-46-1

473268-46-1

473268-46-1 Structure

473268-46-1 Structure
IdentificationBack Directory
[Name]

ADDA 5 hydrochloride
[CAS]

473268-46-1
[Synonyms]

ADDA-5)
ADDA 5 HCl
ADDA 5 (ADDA5
ADDA 5 hydrochloride
ADDA 5 hydrochloride >=98% (HPLC)
[Molecular Formula]

C24H36ClNO2
[MDL Number]

MFCD02053515
[MOL File]

473268-46-1.mol
[Molecular Weight]

406.01
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMSO : 65 mg/mL (160.10 mM)
[form ]

Solid
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

ADDA 5 hydrochloride has been used as a complex IV inhibitor to study its effects on leptomeningeal derivatives of human breast and lung cancer cells.
[Biological Activity]

ADDA 5 is a potent and selective inhibitor of cytochrome c oxidase (Complex IV) th at depletes the bioenergetics reserve capacity in intact glioma cells. ADDA 5 specifically inhibits the proliferation of chemosensitive and chemoresistant glioma cellswhile sparing non-cancer cells. Additionally ADDA 5 is effective against glioma stem cells.
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