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ChemicalBook--->CAS DataBase List--->473-41-6

473-41-6

473-41-6 Structure

473-41-6 Structure
IdentificationBack Directory
[Name]

tolbutamide sodium
[CAS]

473-41-6
[Synonyms]

tolbutamide sodium
TolbutaMide sodiuM salt
Benzenesulfonamide, N-(butylamino)carbonyl-4-methyl-, monosodium salt
[Molecular Formula]

C12H18N2NaO3S
[MDL Number]

MFCD01676730
[MOL File]

473-41-6.mol
[Molecular Weight]

293.338
Chemical PropertiesBack Directory
[Melting point ]

130-133°; mp 41-43°
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[form ]

Powder
Hazard InformationBack Directory
[General Description]

Tolbutamide sodium,1-butyl-3-(p-tolylsulfonyl)urea monosodium salt (OrinaseDiagnostic), is a white, crystalline powder, freely soluble inwater, soluble in alcohol and chloroform, and very slightlysoluble in ether.
[Clinical Use]

This water-soluble salt of tolbutamide is used intravenouslyfor the diagnosis of mild diabetes mellitus and offunctioning pancreatic islet cell adenomas. The sterile drypowder is dissolved in sterile water for injection to make aclear solution, which then should be administered within1 hour. The main route of breakdown is to butylamine andsodium p-toluene sulfonamide.
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