| Identification | Back Directory | [Name]
Steviol | [CAS]
471-80-7 | [Synonyms]
STEVIOL
STEVIOL(P)
NSC 226902
Stevioside
Steviol Standard
Steviol USP/EP/BP
Stevioside 471-80-7
Steviol hydrate
HYDROXYDEHYDROSTEVIC ACID
1H-2,10a-Ethanophenanthrene
(14-alpha)-kaur-16-en-18-oicaci
13-hydroxy-kaur-16-en-18-oicaci
13-HYDROXYKAUR-16-EN-18-OIC ACID
Steviol, 98%, from Stevia rebaudiana
(4R)-13-Hydroxykaur-16-en-18-oic acid
(4α)-13-Hydroxykaur-16-en-18-oic acid
ent-13-Hydroxykauran-16-en-19-oic acid
Steviol glycoside with 80-95% stevioside
(4alpha)-13-Hydroxykaur-16-en-18-oic acid
Kaur-16-en-18-oic acid,13-hydroxy-, (4a)-
(14-alpha)-13-hydroxykaur-16-en-18-oicacid
2,3,4,4aα,4b,5,6,7,8,8aα,9,10-Dodecahydro-2β-hydroxy-4bβ,8α-dimethyl-12-methylene-1H-2α,10aα-ethanophenanthrene-8β-carboxylic acid | [Molecular Formula]
C20H30O3 | [MDL Number]
MFCD00210558 | [MOL File]
471-80-7.mol | [Molecular Weight]
318.45 |
| Chemical Properties | Back Directory | [Melting point ]
215° | [alpha ]
D -94.7° | [Boiling point ]
464.5±45.0 °C(Predicted) | [density ]
1.17±0.1 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,2-8°C | [solubility ]
DMSO: >10mg/mL | [form ]
powder | [pka]
4.65±0.60(Predicted) | [color ]
white to tan | [Stability:]
Light Sensitive | [InChIKey]
QFVOYBUQQBFCRH-ZPNQOMQUSA-N | [LogP]
4.035 (est) |
| Hazard Information | Back Directory | [Uses]
Has been proposed as non-nutritive sweetening agent. | [Definition]
ChEBI: Steviol is an ent-kaurane diterpenoid that is 5beta,8alpha,9beta,10alpha-kaur-16-en-18-oic acid in which the hydrogen at position 13 has been replaced by a hydroxy group. It has a role as an antineoplastic agent. It is a tetracyclic diterpenoid, a tertiary allylic alcohol, a monocarboxylic acid, a bridged compound and an ent-kaurane diterpenoid. It is a conjugate acid of a steviol(1-). | [Health Hazard]
Steviol has been reported to be mutagenic.Wide use of stevia in Japan for >30 years did not produce any known deleterious side effects. In Japan, enzymatically glycosylated blend of stevioside and rebaudioside A, which appears to impart a cleaner taste profile, is also available commercially. | [Biochem/physiol Actions]
Steviol is an inhibitor of hOAT1 and hOAT3 organic anion transporters. Human organic anion transporter hOAT1 belongs to a superfamily of organic anion transporters, which play critical roles in the body disposition of clinically important drugs including anti-HIV therapeutics, anti-tumor drugs, antibiotics, anti-hypertensives, and anti-inflammatories. Steviol is a useful tool for studying renal drug clearance. |
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