Identification | Back Directory | [Name]
MP-412 | [CAS]
451492-95-8 | [Synonyms]
AV-412 MP-412 CS-2307 MP-412 free base AV-412 (free base) AV-412 free base (MP-412 free base) AV-412;MP-412;AV 412;MP 412;AV412;MP412 N-(4-((3-Chloro-4-fluorophenyl)amino)-7-(3-methyl-3-(4-methylpiperazin-1-yl)but-1-yn-1-yl)quin N-[4-(3-chloro-4-fluoroanilino)-7-[3-methyl-3-(4-methylpiperazin-1-yl)but-1-ynyl]quinazolin-6-yl]prop-2-enamide N-(4-((3-chloro-4-fluorophenyl)amino)-7-(3-methyl-3-(4-methylpiperazin-1-yl)but-1-yn-1-yl)quinazolin-6-yl)acrylamide N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[3-methyl-3-(4-methyl-1-piperazinyl)-1-butyn-1-yl]-6-quinazolinyl]-2-propenamide 2-PropenaMide, N-[4-[(3-chloro-4-fluorophenyl)aMino]-7-[3-Methyl-3-(4-Methyl-1-piperazinyl)-1-butyn-1-yl]-6-quinazolinyl]- | [Molecular Formula]
C27H28ClFN6O | [MDL Number]
MFCD16038939 | [MOL File]
451492-95-8.mol | [Molecular Weight]
507 |
Chemical Properties | Back Directory | [Boiling point ]
672.9±55.0 °C(Predicted) | [density ]
1.33 | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: ≥ 50 mg/mL (98.62 mM) | [form ]
Powder | [pka]
11.61±0.43(Predicted) | [color ]
White to yellow |
Hazard Information | Back Directory | [Uses]
AV 412 is used in the synthetic preparation of phenylaminoquinazoline derivatives as inhibitors of tyrosine-specific protein kinase for preparation and/or treatment of cancers, diseases caused by arteriosclerosis, or psoriasis. |
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