| Identification | Back Directory | [Name]
N-mesityl-2-(3-oxoindeno[1,2,3-de]phthalazin-2(3H)-yl)acetamide | [CAS]
445218-34-8 | [Synonyms]
N-mesityl-2-(3-oxoindeno[1,2,3-de]phthalazin-2(3H)-yl)acetamide | [Molecular Formula]
C25H21N3O2 | [MOL File]
445218-34-8.mol | [Molecular Weight]
395.453 |
| Hazard Information | Back Directory | [Biological Activity]
Brain tissue penetrant alpha-synuclein ligand th at potently disaggregate alpha-synuclein fibrils in vitro and in vivo models.
CNS-11 is brain tissue penetrant alpha-synuclein ligand th at potently disaggregate alpha-synuclein fibrils in vitro and in vivo models. CNS-11 inhibits intracellular seeding of a-synuclein fibrils in biosensor cells—HEK293T cells. C-11 reduces number of a-synuclein aggregates in C. elegans model. |
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