| Identification | Back Directory | [Name]
Ligustilide | [CAS]
4431-01-0 | [Synonyms]
LIGUSTILIDE
Z-LIGUSTILIDE
LIGUSTILIDE, Z-
Ligustilide Oil
Angelica Extract Powder
Ligusticum chuanxiong oil
Angelic(sinensis (Oilv)Diels
Angelica tsinlingensis absolute
3-BUTYLIDENE-4,5-DIHYDROPHTHALIDE
3-[(Z)-Butylidene]-4,5-dihydrophthalide
3-BUTYLIDEN-4,5-DIHYDRO-3H-ISOBENZOFURAN-1-ONE
Ligustilide
3-Butylidene-4,5-dihydrophthalide
3-Butylidene-4,5-dihydro-1(3H)-isobenzofuranone
3-Butylidene-4,5-dihydroisobenzofuran-1(3H)-one
1(3H)-Isobenzofuranone,3-butylidene-4,5-dihydro-
LIGUSTILIDE, Z-(IN ACETONITRILE)(1.0227mg/mL)(AHP)
3-BUTYLIDENE-4,5-DIHYDROPHTHALIDE
ANGELICA EXTRACT
(3Z)-3-Butylidene-4,5-dihydroisobenzofuran-1(3H)-one
Ligustilide, 98%, from Angelica sinensis (Oliv.) Diels
3-[(Z)-Butylidene]-1,3,4,5-tetrahydroisobenzofuran-1-one | [Molecular Formula]
C12H14O2 | [MDL Number]
MFCD01861511 | [MOL File]
4431-01-0.mol | [Molecular Weight]
190.24 |
| Chemical Properties | Back Directory | [Boiling point ]
377.9±11.0 °C(Predicted) | [density ]
1.10±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C, protect from light, stored under nitrogen | [solubility ]
DMSO : 100 mg/mL (525.65 mM; Need ultrasonic) | [form ]
Oil | [Stability:]
Light Sensitive | [LogP]
1.710 (est) |
| Hazard Information | Back Directory | [Uses]
Ligustilide, is a dihydrophthalide, and an active ingredients of umbelliferous plants as Angelica sinensis and Ligusticum chuanxiong, having wide range of pharmacology effects on neuroprotection, vasodilatation, anti-caner and anti-tumor, analgesia and anti-inflammation. | [Definition]
ChEBI: A natural product found in Ligusticum porteri. | [Biological Activity]
Ligustilide can inhibit the proliferation of and cell cycle progression of vascular smooth muscle cells and inhibits vasoconstriction. It increases vasodilationanti-thrombosisand serotonergic activity and decreases platelet aggregation. It has been shown to have broad applications in the study and treatment of cardiovascular diseases and ischemic brain injury. Ligustilide has the ability to reduce neurogenic and inflammatory pain. Thusit can be used as a potential therapeutic agent to tre at several pain syndromes including primary dysmenorrhoea. |
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