| Identification | Back Directory | [Name]
Hydrazinecarbothioamide, 2-[1-(2-thienyl)ethylidene]-, (2Z)- | [CAS]
433212-75-0 | [Synonyms]
SSAA09E1
SSAA09E1 [(Z)-1-Thiophen-2-ylethylideneamino]thiourea
Hydrazinecarbothioamide, 2-[1-(2-thienyl)ethylidene]-, (2Z)- | [Molecular Formula]
C7H9N3S2 | [MOL File]
433212-75-0.mol | [Molecular Weight]
199.3 |
| Chemical Properties | Back Directory | [Boiling point ]
333.0±34.0 °C(Predicted) | [density ]
1.37±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Ethanol: soluble | [form ]
A crystalline solid | [pka]
11.50±0.70(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
SSAA09E1 is a cathepsin L blocker (IC50: 5.33 μM).SSAA09E1 inhibits stages of viral entry. SSAA09E1 can be used for SARS-CoV infection research[1] | [Biological Activity]
SSAA09E1 is an inhibitor of severe acute respiratory syndrome coronavirus (SARS-CoV) viral entry.1 It reduces infection of HEK293T cells transiently transfected with angiotensin-converting enzyme 2 (ACE2) by an HIV-based virus system pseudotyped with SARS-CoV surface glycoprotein (EC50 = 6.7 μM). SSAA09E1 also inhibits the proteolytic activity of cathepsin L (IC50 = 5.33 μM) but not cathepsin B when used at a concentration of 20 μM. | [References]
1.()
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| Company Name: |
ChemeGen 中國
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| Tel: |
18818260767 |
| Website: |
https://www.chemegen.com |
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