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ChemicalBook--->CAS DataBase List--->427-63-4

427-63-4

427-63-4 Structure

427-63-4 Structure
IdentificationBack Directory
[Name]

GEODIN
[CAS]

427-63-4
[Synonyms]

GEODIN
d-Geodin
(+)-ESTIN
(+)-Form methyl ester
methyl 5,7-dichloro-4-hydroxy-5'-methoxy-6-methyl-3,3'-dioxospiro[1-benzofuran-2,6'-cyclohexa-1,4-diene]-1'-carboxylate
methyl 5,7-dichloro-4-hydroxy-5'-methoxy-6-methyl-3,3'-dioxo-spiro[1-benzofuran-2,6'-cyclohexa-1,4-diene]-1'-carboxylate
5,7-dichloro-4-hydroxy-3,3'-diketo-5'-methoxy-6-methyl-spiro[benzofuran-2,6'-cyclohexa-1,4-diene]-1'-carboxylic acid methyl ester
SPIRO[BENZOFURAN-2(3H),1'-[2,5]CYCLOHEXADIENE]-2'-CARBOXYLIC ACID, 5,7-DICHLORO-4-HYDROXY-6'-METHOXY-6-METHYL-3,4'-DIOXO-, METHYL ESTER
(R)-5,7-Dichloro-4-hydroxy-6'-methoxy-6-methyl-3,4'-dioxospiro[benzofuran-2(3H),1'-[2,5]cyclohexadiene]-2'-carboxylic acid methyl ester
(1R)-3',4-Dioxo-4'-hydroxy-5',7'-dichloro-6-methoxy-6'-methylspiro[2,5-cyclohexadiene-1,2'(3'H)-benzofuran]-2-carboxylic acid methyl ester
(1R)-3',4-Dioxo-4'-hydroxy-5',7'-dichloro-6'-methyl-6-methoxyspiro[2,5-cyclohexadiene-1,2'(3'H)-benzofuran]-2-carboxylic acid methyl ester
(1'R)-3,4'-Dioxo-5,7-dichloro-4-hydroxy-6'-methoxy-6-methyl-spiro[benzofuran-2(3H),1'-[2,5]cyclohexadiene]-2'-carboxylic acid methyl ester
Estin, (+)-5,7-dichloro-4-hydroxy-6-methoxy-6-methyl-3,4-dioxo-spiro[benzofuran-2(3H),1-[2,5]cyclohexadiene]-2-carboxylic acid methyl ester
[Molecular Formula]

C17H12Cl2O7
[MDL Number]

MFCD00600308
[MOL File]

427-63-4.mol
[Molecular Weight]

399.18
Chemical PropertiesBack Directory
[Melting point ]

235℃
[alpha ]

D +140° (c = 0.8)
[storage temp. ]

Store at -20°C
[solubility ]

Chloroform: soluble; DMSO: soluble; Ethyl Acetate: soluble; Methanol: soluble
[form ]

A solid
[color ]

Yellow
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302+H312+H332
[Precautionary statements ]

P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P321-P330-P362+P364-P501
Hazard InformationBack Directory
[Description]

(+)-Geodin is a fungal metabolite. It increases the fibrinolytic activity of bovine aortic endothelial cells (BAECs) when used at concentrations ranging from 50 to 150 μM. (+)-Geodin (1-100 μg/ml) also increases 2-deoxyglucose uptake by rat adipocytes.
[Uses]

Geodin is an inhibitor of plasminogen activator inhibitor (PAI-1).
[storage]

Store at -20°C
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