Identification | Back Directory | [Name]
NS 5806 | [CAS]
426834-69-7 | [Synonyms]
NS 5806 N-[3,5-bis(trifluoromethyl)phenyl]-N′-[2,4-dibromo-6-(1H-tetrazol-5-yl)phenyl]-urea N-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]--N'-[2,4-DIBROMO-6-(2H-TETRAZOL-5-YL)PHENYL]UREA Urea, N-[3,5-bis(trifluoromethyl)phenyl]-N'-[2,4-dibromo-6-(2H-tetrazol-5-yl)phenyl]- | [Molecular Formula]
C16H8Br2F6N6O | [MDL Number]
MFCD18432708 | [MOL File]
426834-69-7.mol | [Molecular Weight]
574.07 |
Hazard Information | Back Directory | [Biochem/physiol Actions]
NS5806 increases peak current amplitude of the potassium channel Kv4.3 (EC50 = 5.3 uM). NS5806 also slows Kv4.3 and Kv4.2 current dacay in channel complexes containing KChIP2. In ventricular cardiomycytes, NS5806 increases transient outward current and reproduces the electrocardiographic profile of Brugada syndrome. | [storage]
Store at -20°C |
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