成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

ChemicalBook--->CAS DataBase List--->423148-46-3

423148-46-3

423148-46-3 Structure

423148-46-3 Structure
IdentificationBack Directory
[Name]

SBC-115337
[CAS]

423148-46-3
[Synonyms]

SBC-115337
[Molecular Formula]

C29H19N3O4
[MDL Number]

MFCD02210564
[MOL File]

423148-46-3.mol
[Molecular Weight]

473.48
Chemical PropertiesBack Directory
[Boiling point ]

539.4±40.0 °C(Predicted)
[density ]

1.394±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[form ]

Solid
[pka]

12.36±0.70(Predicted)
[color ]

Light yellow to brown
Spectrum DetailBack Directory
[Spectrum Detail]

SBC-115337(423148-46-3)1HNMR
Hazard InformationBack Directory
[Biological Activity]

SBC-115337, as a potent benzofuran compound, is a PCSK9 inhibitor with an IC50 value of 0.5 μM[1][2]. The potent compound (SBC-115,337) shows an IC50 of 0.6 μM measured in an in vitro ELISA assay to monitor the effect of PCSK9 binding to the recombinant LDLR. SBC-115,337 at 1.2 μM induces more than tenfold upregulation of LDLR in HepG2 cells with respect to the control, increases uptake of fluorescently labeled DiI-LDL and loweres LDL-c levels in mice fed a high-fat diet[2].
[References]

[1]. Xu S, et al. Small molecules as inhibitors of PCSK9: Current status and future challenges. Eur J Med Chem. 2019;162:212-233. [2]. Lavecchia A, et al. Recent advances in developing PCSK9 inhibitors for lipid-lowering therapy. Future Med Chem. 2019;11(5):423-441.
423148-46-3 suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000 , +1-00000000000
Website: https://www.targetmol.com/
Company Name: TargetMol Chemicals Inc.
Tel:
Website: www.targetmol.com/
Company Name: Tianjin Kailiqi Biotechnology Co., Ltd.  
Tel: 15076683720
Website: http://www.cw-bio.com
Company Name: Bide Pharmatech Ltd.  
Tel: 400-1647117 13681763483
Website: https://www.bidepharm.com/
Company Name: TargetMol Chemicals Inc.  
Tel: 4008200310
Website: https://www.targetmol.cn/
Company Name: Nanjing Tengyi Biotechnology Co., Ltd  
Tel: 025-58851786 17714337195
Website: https://tybiochem.com/
Company Name: Shanghai Yifei Biotechnology Co. , Ltd.  
Tel: 021-65675885 18964387627
Website: http://www.efebio.com
Company Name: RD International Technology Co., Limited  
Tel: 18024082417
Website: www.ruidiresearch.com
Company Name: Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd  
Tel: 025-58851090 13915962545
Website: www.aikonchem.com/
Company Name: nanjing  
Tel: 13376082704 13376082704
Website: www.linye-e.com/
Company Name: Sangon Biotech (Shanghai) Co.,Ltd.  
Tel: 400-821-026
Website: www.sangon.com
Company Name: Absin Bioscience Inc.  
Tel: 021-38015121-8802
Website: http://www.absin.cn
Company Name: Proteintech China  
Tel: 027-87531629
Website: http://www.ptgcn.com
Tags:423148-46-3 Related Product Information

This site uses cookies
This website uses cookies and similar technologies to store and retrieve information about your use of this website. This information helps us to provide, analyse and improve our services, which may include personalised content or advertising. We may share this information with Google and other third parties. This cookies are necessary for our website to work properly . By clicking "Continue" or continuing to browse our site you are agreeing to our and our partners use of cookies.
Accept