| Identification | Back Directory | [Name]
BAM (8-22) | [CAS]
412961-36-5 | [Synonyms]
BAM (8-22)
BAM-22P (8-22)
Bovine Adrenal Medulla 8-22
BAM8-22 trifluoroacetate salt
BAM (8-22) trifluoroacetate salt
VGRPEWWMDYQKRYG trifluoroacetate salt
Bovine Adrenal Medulla 8-22 trifluoroacetate salt
Bovine adrenal medulla peptide (8-22) trifluoroacetate salt
Val-Gly-Arg-Pro-Glu-Trp-Trp-Met-Asp-Tyr-Gln-Lys-Arg-Tyr-Gly
Val-Gly-Arg-Pro-Glu-Trp-Trp-Met-Asp-Tyr-Gln-Lys-Arg-Tyr-Gly trifluoroace
BAM-22P (8-22) trifluoroacetate salt H-Val-Gly-Arg-Pro-Glu-Trp-Trp-Met-Asp-Tyr-Gln-Lys-Arg-Tyr-Gly-OH trifluoroacetate salt
L-Valyl-glycyl-L-arginyl-L-prolyl-L-α-glutamyl-L-tryptophyl-L-tryptophyl-L-methionyl-L-α-aspartyl-L-tyrosyl-L-glutaminyl-L-lysyl-L-arginyl-L-tyrosyl-glycine trifluoroacetate salt | [Molecular Formula]
C91H127N25O23S | [MDL Number]
MFCD04974822 | [MOL File]
412961-36-5.mol | [Molecular Weight]
1971.2 |
| Hazard Information | Back Directory | [Uses]
BAM8-22 trifluoroacetate salt has been used in the study to identify the functions of Mas-related gene (Mrg) C in the pathogenesis and treatment of bone cancer pain (BCP). | [Biochem/physiol Actions]
BAM8-22 is a selective agonist for the sensory neuron specific G-protein coupled receptors (SNSRs). BAM8-22 inhibits development of morphine tolerance in rats. BAM8-22 is inactive at opioid receptors. Also, BAM8–22 is a potent activator of Mas-related G-protein-coupled receptors (Mrgprs), MrgprC11 and hMrgprX1. BAM8-22 produces itch and nociceptive sensations in humans in a histamine-independent manner. | [storage]
-20°C (desiccate) |
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