| Identification | Back Directory | [Name]
Razaxaban (Hydrochloride) | [CAS]
405940-76-3 | [Synonyms]
DPC906
DPC 906
BMS 561389
DPC 906 hydrochloride
BMS 561389 hydrochloride
Razaxaban (Hydrochloride)
2-(3-amino-1,2-benzoxazol-5-yl)-N-[4-[2-[(dimethylamino)methyl]imidazol-1-yl]-2-fluorophenyl]-5-(trifluoromethyl)pyrazole-3-carboxamide:hydrochloride | [Molecular Formula]
C24H21ClF4N8O2 | [MDL Number]
MFCD25976560 | [MOL File]
405940-76-3.mol | [Molecular Weight]
564.923 |
| Hazard Information | Back Directory | [Uses]
Anticoagulant; antithrombotic (Factor Xa
inhibitor). | [in vivo]
Razaxaban (Compound 11d; 0.21-9.4 mg/kg/hour; intravenous injection) inhibits thrombus formation in a dose-dependent manner with an ID50 of 1.6 μmol/kg/h in the rabbit arterio-venous shunt thrombosis model[1]. | Animal Model: | Rabbit arterio-venous shunt thrombosis model[1] | | Dosage: | 0.21 mg/kg/hour, 0.7 mg/kg/hour, 2.1 mg/kg/hour, 9.4 mg/kg/hour | | Administration: | Intravenous injection | | Result: | Inhibited thrombus formation in a dose-dependent manner with an ID50 of 1.6 μmol/kg/h.
|
|
|
| Company Name: |
MedChemExpress
|
| Tel: |
021-58955995 |
| Website: |
www.medchemexpress.com |
|