| Identification | Back Directory | [Name]
Ethanone, 1-(1,4-dihydroxy-2-naphthalenyl)- | [CAS]
40420-48-2 | [Synonyms]
4-NHQ
2-Mc-1
NSC111552
NSC-111552
NSC 111552
2-Mc-1,4-NHQ
2Mc1,4NHQ,2 Mc 1,4 NHQ
Ethanone, 1-(1,4-dihydroxy-2-naphthalenyl)-
1-(1,4-Dihydroxynaphthalen-2-yl)ethan-1-one | [Molecular Formula]
C12H10O3 | [MDL Number]
MFCD00598701 | [MOL File]
40420-48-2.mol | [Molecular Weight]
202.21 |
| Hazard Information | Back Directory | [Uses]
NSC111552 is a potent SARS-CoV-2 NSP14 MTase inhibitor. NSC111552 inhibits the FL-NAH binding to the SARS-CoV-2 NSP14 MTase with an IC50 of 5.1 μM[1]. | [References]
[1] Samrat SK, et al. A universal fluorescence polarization high throughput screening assay to target the SAM-binding sites of SARS-CoV-2 and other viral methyltransferases. Emerg Microbes Infect. 2023 Dec;12(1):2204164. DOI:10.1080/22221751.2023.2204164 |
|
|