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ChemicalBook--->CAS DataBase List--->402713-80-8

402713-80-8

402713-80-8 Structure

402713-80-8 Structure
IdentificationBack Directory
[Name]

SB 399885 HYDROCHLORIDE
[CAS]

402713-80-8
[Synonyms]

CS-1610
SB399885
SB-399885
SB 399885
SB 399885 HCl
SB 399885 HYDROCHLORIDE
SB399885 HCl,SB-399885 HCl
SB-399885;SB 399885;SB399885
SB399885 Hydrochloride|||SB 399885|||SB399885|||SB-399885
N-(3,5-dichloro-2-methoxyphenyl)-4-methoxy-3-(1-piperazinyl)benzenesulfonamide
N-(3,5-Dichloro-2-methoxyphenyl)-4-methoxy-3-(piperazin-1-yl)benzenesulfonamide
Benzenesulfonamide, N-(3,5-dichloro-2-methoxyphenyl)-4-methoxy-3-(1-piperazinyl)-
N-(3,5-Dichloro-2-methoxyphenyl)-4-methoxy-3-(1-piperazinyl)benzenesulfonamidehydrochloride
[Molecular Formula]

C18H21Cl2N3O4S
[MDL Number]

MFCD11519963
[MOL File]

402713-80-8.mol
[Molecular Weight]

446.35
Chemical PropertiesBack Directory
[storage temp. ]

Desiccate at RT
[solubility ]

DMSO: 100mM
water: 100mM
[form ]

solid
[color ]

white
Hazard InformationBack Directory
[Uses]

SB 399885 Hydrochloride is a selective 5-HT6 receptor antagonist.
[Biological Activity]

Potent, brain penetrant, orally active 5-HT 6?antagonist. Displays > 200-fold selectivity for 5-HT 6?over other 5-HT receptors (pK i values are 9.11, 8.81 and 9.02? for human recombinant, native rat and native human 5-HT 6 receptors respectively).
[IC 50]

5-HT6 Receptor: 9.02 (pKi); Human 5-HT6 Receptor: 9.11 (pKi)
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