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ChemicalBook--->CAS DataBase List--->402616-26-6

402616-26-6

402616-26-6 Structure

402616-26-6 Structure
IdentificationBack Directory
[Name]

(S) FTY720 PHOSPHATE
[CAS]

402616-26-6
[Synonyms]

(S)-FTY720-
(S)-FTY720-P
FTY720 (S)-Phosphate
(S) FTY720 PHOSPHATE
(2S)-2-Amino-2-[2-(4-octylphenyl)ethyl]-1-(dihydrogen phosphate)-1,3-propanediol)
2-(S)-Amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol Mono(dihydrogen phosphate) Ester
[Molecular Formula]

C19H34NO5P
[MOL File]

402616-26-6.mol
[Molecular Weight]

387.454
Chemical PropertiesBack Directory
[Appearance]

White Solid
[Melting point ]

184-186°C
[Boiling point ]

584.2±60.0 °C(Predicted)
[density ]

1.172±0.06 g/cm3(Predicted)
[storage temp. ]

-20°C Freezer
[solubility ]

DMSO: soluble0.3mg/mL, clear (warmed)
[form ]

Solid
[pka]

1.73±0.10(Predicted)
[color ]

white to beige
Hazard InformationBack Directory
[Chemical Properties]

White Solid
[Uses]

A sphingosine 1-phosphate receptor modular, ameliorates experimental autoimmune encephalomyelitis by inhibition of T cell infiltration. It is the active metabolite of FTY720-phosphate
[Uses]

FTY720 is a sphingosine 1-phosphate receptor modular, ameliorates experimental autoimmune encephalomyelitis by inhibition of T cell infiltration. FTY720 Phosphate is the active metabolite of FTY720- phosphate.
[in vivo]

FTY720 (S)-Phosphate (0.5 mg/kg, i.p.) preserves S1PR1 expression in mouse lungs, is protective in bleomycin-induced acute lung injury (ALI) and attenuates lung tissue leukocyte infiltration in bleomycin-injured mice[1].

Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335-H336
[Precautionary statements ]

P261-P264-P270-P271-P280-P301+P312-P330-P302+P352-P321-P304+P340-P305+P351+P338-P332+P313-P362+P364-P337+P313-P403+P233-P405-P501
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