| Identification | Back Directory | [Name]
3-fluoro-N'-[(E)-(5-nitrothiophen-2-yl)methylidene]benzohydrazide | [CAS]
394694-98-5 | [Synonyms]
MitoBloCK-10 (MB-10)
3-fluoro-N'-[(E)-(5-nitrothiophen-2-yl)methylidene]benzohydrazide
Benzoic acid, 3-fluoro-, 2-[(5-nitro-2-thienyl)methylene]hydrazide | [Molecular Formula]
C12H8FN3O3S | [MDL Number]
MFCD00813373 | [MOL File]
394694-98-5.mol | [Molecular Weight]
293.27 |
| Chemical Properties | Back Directory | [density ]
1.47±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: 2mg/mL, clear | [form ]
Solid | [pka]
11.21±0.46(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Biological Activity]
Mitochondrial import blocker of substances requiring inner membrane translocon TIM23.
MitoBloCK-10 (MB-10) is mitochondrial import blocker of substances requiring inner membrane translocon TIM23 (TIM23) in yeast and mammalian mitochondria. It appears th at MB-10 targets Tim44 of the PAM complex. MitoBloCK-10 does not alter respiraton. MB-10 inhibits cardiac development and induces apoptosis in Zebrafish embryos. It inhibits bladder cancer cell growth in vitro and in vivo. |
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| Company Name: |
InvivoChem
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| Tel: |
13549236410 |
| Website: |
https://www.invivochem.cn/ |
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