| Identification | Back Directory | [Name]
5-Pyrimidinecarboxylic acid, 6-(3,4-difluorophenyl)-1,2,3,6-tetrahydro-4-(methoxymethyl)-2-oxo-1-[[[3-[4-(2-pyridinyl)-1-piperidinyl]propyl]amino]carbonyl]-, methyl ester | [CAS]
391610-37-0 | [Synonyms]
MCHr1 antagonist 1
methyl 4-(3,4-difluorophenyl)-6-(methoxymethyl)-2-oxo-3-((3-(4-(pyridin-2-yl)piperidin-1-yl)propyl)carbamoyl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate
5-Pyrimidinecarboxylic acid, 6-(3,4-difluorophenyl)-1,2,3,6-tetrahydro-4-(methoxymethyl)-2-oxo-1-[[[3-[4-(2-pyridinyl)-1-piperidinyl]propyl]amino]carbonyl]-, methyl ester | [Molecular Formula]
C28H33F2N5O5 | [MDL Number]
MFCD31382100 | [MOL File]
391610-37-0.mol | [Molecular Weight]
557.589 |
| Hazard Information | Back Directory | [Description]
MCHr1 antagonist 1 is a selective antagonist of melanin concentrating hormone-1 (MCH1) receptor, with a Kb of 1 nM and a Ki of 4 nM at human MCH1, and may be used to reduce the body mass. MCHr1 antagonist 1 shows potent activities against melanin concentrating hormone-1 receptor, but less potent against human MCH1, NPY1, NPY5, GALR1, GALR2, GALR3, and rat 5HT2C receptors, with Kis of >50000 nM[1]. | [References]
[1]. Selective melanin concentrating hormone-1 (MCH1) receptor antagonists and uses thereof. US 20030069261 A1 |
|
| Company Name: |
BOC Sciences
|
| Tel: |
|
| Website: |
https://www.bocsci.com |
|