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ChemicalBook--->CAS DataBase List--->390800-88-1

390800-88-1

390800-88-1 Structure

390800-88-1 Structure
IdentificationBack Directory
[Name]

2-PyrazinecarboxaMide, N,N',N''-[2,4,6-boroxintriyltris[[(1R)-3-Methylbutylidene]iMino[(1S)-2-oxo-1-(phenylMethyl)-2,1-ethanediyl]]]tris-
[CAS]

390800-88-1
[Synonyms]

Bortezomib-d15
Bortezomib Trimer
(1R,2S)-Bortezomib
Bortezomib trimer API
Bortezomib ((1R,2S)-Bortezomib)
Bortezomib impurity 10/(1R,2S)-Bortezomib
Bortezomib Trimer ((1R,2S)-Bortezomib Trimer)
2-PyrazinecarboxaMide, N,N',N''-[2,4,6-boroxintriyltris[[(1R)-3-Methylbutylidene]iMino[(1S)-2-oxo-1-(phenylMethyl)-2,1-ethanediyl]]]tris-
[EINECS(EC#)]

816-310-1
[Molecular Formula]

C57H69B3N12O9
[MDL Number]

MFCD32644677
[MOL File]

390800-88-1.mol
[Molecular Weight]

1098.67
Chemical PropertiesBack Directory
[Boiling point ]

1277.7±65.0 °C(Predicted)
[density ]

1.26±0.1 g/cm3(Predicted)
[storage temp. ]

-20°C Freezer
[pka]

11.46±0.46(Predicted)
Safety DataBack Directory
[Symbol(GHS) ]


GHS08,GHS09,GHS06
[Signal word ]

Danger
[Hazard statements ]

H361-H300-H372-H315-H411-H319
[Precautionary statements ]

P201-P202-P281-P308+P313-P405-P501-P260-P264-P270-P314-P501-P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P-P264-P270-P301+P310-P321-P330-P405-P501
Hazard InformationBack Directory
[Uses]

Bortezomib Trimer is derived from Bortezomib (B675700), which is the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway.
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