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ChemicalBook--->CAS DataBase List--->389128-28-3

389128-28-3

389128-28-3 Structure

389128-28-3 Structure
IdentificationBack Directory
[Name]

(2R,5S)-5-(3,4-Dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic Acid (1R,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexyl Ester
[CAS]

389128-28-3
[Synonyms]

Lamivudine Impurity 27
Lamivudine Impurity 32
Lamivudine Impurity 25
(2RS,5RS)-(1R,2S,5R)-2-isopropyl-5-methylcyclohexyl 5-(4-amino-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolane-2-carboxylate
(2R,5S)-(1R,2S,5R)-2-isopropyl-5-methylcyclohexyl 5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-1,3-oxathiolane-2-carboxylate
(2R,5S)-5-(3,4-Dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic Acid (1R,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexyl Ester
[Molecular Formula]

C18H26N2O5S
[MOL File]

389128-28-3.mol
[Molecular Weight]

382.474
Chemical PropertiesBack Directory
[form ]

Solid
[color ]

White
Hazard InformationBack Directory
[Uses]

(2R,5S)-5-(3,4-Dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic Acid (1R,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexyl Ester is an intermediate in the synthesis of (2R-cis)-1-[2-(Hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)-pyrimidinedione which is an impurity of Lamivudine (L172500). (2R-cis)-1-[2-(Hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)-pyrimidinedione is also being further studied to determine its potential as an anti-HIV agent.
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