| Identification | Back Directory | [Name]
ethyl 2-amino-7-hydroxy-4-(4-nitrophenyl)-4H-chromene-3-carboxylate | [CAS]
374102-08-6 | [Synonyms]
WAY-300916
Aminopeptidase-IN-1
ethyl 2-amino-7-hydroxy-4-(4-nitrophenyl)-4H-chromene-3-carboxylate
4H-1-Benzopyran-3-carboxylic acid, 2-amino-7-hydroxy-4-(4-nitrophenyl)-, ethyl ester | [Molecular Formula]
C18H16N2O6 | [MOL File]
374102-08-6.mol | [Molecular Weight]
356.33 |
| Hazard Information | Back Directory | [Uses]
Aminopeptidase-IN-1 (compound 16o) is a potent insulin-regulated aminopeptidase (IRAP) inhibitor with an Ki value of 7.7 μM. Aminopeptidase-IN-1 can be used tor research cognitive and memory impairments[1]. | [References]
[1] Mountford SJ, et al. Synthesis, structure-activity relationships and brain uptake of a novel series of benzopyran inhibitors of insulin-regulated aminopeptidase. J Med Chem. 2014 Feb 27;57(4):1368-77. DOI:10.1021/jm401540f |
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