Identification | Back Directory | [Name]
5-Chloro-2-oxo-benzooxazole-3-carboxylic acid phenyl ester | [CAS]
371215-02-0 | [Synonyms]
5-Chloro-2-oxo-benzooxazole-3-carboxylic acid phenyl ester 3(2H)-Benzoxazolecarboxylic acid, 5-chloro-2-oxo-, phenyl ester | [Molecular Formula]
C14H8ClNO4 | [MDL Number]
MFCD01565777 | [MOL File]
371215-02-0.mol | [Molecular Weight]
289.67 |
Hazard Information | Back Directory | [Description]
BZX1 is a novel inhibitor of O-GlcNAc transferase (OGT) activity. | [Uses]
OGT-IN-1 (Compound 5) is a potent OGT inhibitor. OGT-IN-1 inhibits sOGT and ncOGT with IC50s of 27 and 10 μM, respectively[1]. | [References]
[1] Gross BJ, et al. Discovery of O-GlcNAc transferase inhibitors. J Am Chem Soc. 2005 Oct 26;127(42):14588-9. DOI:10.1021/ja0555217 |
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