| Identification | Back Directory | [Name]
GLYCODEOXYCHOLIC ACID | [CAS]
360-65-6 | [Synonyms]
GLYCODEOXYCHOLATE
deoxycholylglycine
glycodeoxycholicaci
GLYCODEOXYCHOLIC ACID
DEOXYGLYCOCHOLIC ACID
glykodesoxycholsaeure
GLYCODESOXYCHOLIC ACID
Glycodeoxycholic acid hydrate
deoxycholicacidglycineconjugate
GLYCODEOXYCHOLIC ACID FREE ACID
GDCA)Glycodeoxycholic acid Monohy
glycodeoxy-5-beta-cholan-24-oicaci
Glycodeoxycholic acid Monohydrate (GDCA)
N-(3a,12a-Dihydroxy-24-oxocholan-24-yl)glycine
N-(3α,12α-Dihydroxy-24-oxocholan-24-yl)glycine
N-(3α,12α-Dihydroxy-24-oxo-5β-cholan-24-yl)glycine
N-(3α,12α-Dihydroxy-24-oxo-5β-cholane-24-yl)glycine
N-Carboxymethyl-3α,12α-dihydroxy-5β-cholane-24-amide
N-[3ALPHA,12ALPHA-DIHYDROXY-24-OXOCHOLAN-24-YL]GLYCINE
N-[(3a,5b,12a)-3,12-dihydroxy-24-oxocholan-24-yl]-Glycine
n-(3-alpha,12-alpha-dihydroxy-5-beta-cholan-24-yl)-glycin
3α,12α-Dihydroxy-5β-cholanoic acid N-(carboxymethyl)amide
Glycine, N-[(3α,5β,12α)-3,12-dihydroxy-24-oxocholan-24-yl]-
5BETA-CHOLANIC ACID-3ALPHA,12ALPHA-DIOL-24-N-(CARBOXYETHYL)-AMIDE
5-BETA-CHOLANIC ACID-3-ALPHA, 12-ALPHA-DIOL N-(CARBOXYMETHYL)-AMIDE
5BETA-CHOLAN-24-OIC ACID N-[CARBOXYMETHYL]AMIDE-3ALPHA,12ALPHA-DIOL
n-((3-alpha,5-beta,12-alpha)-3,12-dihydroxy-24-oxocholan-24-yl)-glycine
3ALPHA,12ALPHA-DIHYDROXY-5BETA-CHOLAN-24-OIC ACID N-[CARBOXYMETHYL]AMIDE
3α,12α-Dihydroxy-5β-cholanoic acid N-(carboxymethyl)amide, Glycodesoxycholic acid, N-(3α,12α-Dihydroxy-24-oxocholan-24-yl)glycine
Glycodesoxycholic acid, N-(3α,12α-Dihydroxy-24-oxocholan-24-yl)glycine, 3α,12α-Dihydroxy-5β-cholanoic acid N-(carboxymethyl)amide
3α,12α-Dihydroxy-5β-cholanoic acid N-(carboxymethyl)amide
Glycodesoxycholic acid
N-(3α,12α-Dihydroxy-24-oxocholan-24-yl)glycine
GDCA
2-((R)-4-((3R,5R,8R,9S,10S,12S,13R,14S,17R)-3,12-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)acetic acid
2-[4-[(3R,5R,10R,12S,13R)-3,12-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentylamino]acetic acid
Glycodeoxycholic acid monohydrate,3α,12α-Dihydroxy-5β-cholanoic acid N-(carboxymethyl)amide, Glycodesoxycholic acid, N-(3α,12α-Dihydroxy-24-oxocholan-24-yl)glycine
2-[4-[(3R,5R,10R,12S,13R)-3,12-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentylamino]ethanoic acid | [Molecular Formula]
C26H43NO5 | [MDL Number]
MFCD00067133 | [MOL File]
360-65-6.mol | [Molecular Weight]
449.63 |
| Chemical Properties | Back Directory | [Melting point ]
184 °C | [Boiling point ]
655.6±50.0 °C(Predicted) | [density ]
1.162±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,2-8°C | [solubility ]
Acetonitrile (Slightly), Ethanol (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
pKa 3.87±0.06(H2O,t = 25.0±0.1,I=0.00) (Uncertain) | [color ]
White to Off-White |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
36/37/38 | [Safety Statements ]
26 | [WGK Germany ]
3
| [RTECS ]
MB9670000
| [F ]
10 | [Toxicity]
mouse,LD50,intravenous,140mg/kg (140mg/kg),Arzneimittel-Forschung. Drug Research. Vol. 20, Pg. 323, 1970. |
| Hazard Information | Back Directory | [Uses]
Glycodeoxycholic Acid is a bile acid that induces severe pancreatitis in rats. | [Definition]
ChEBI: Glycodeoxycholic acid is a bile acid glycine conjugate of deoxycholic acid. It has a role as a human metabolite. It is functionally related to a deoxycholic acid. It is a conjugate acid of a glycodeoxycholate. | [storage]
Store at -20°C | [Purification Methods]
Glycodeoxycholic acid recrystallises from H2O or aqueous EtOH with 1 mol of H2O and is dried at 100o in vacuo. Its solubility in EtOH is ~5%. [UV: Lindstedt & Sj.vall Acta Chem Scand 11 421 1957.] The Na salt recrystallises from EtOH/Et2O with m 245-250o and [] D23 +41.2o (c 1, H2O) [Wieland Hoppe Seyler's Z Physiol Chem 106 181 1919, Cortese J Am Chem Soc 59 2532 1937]. [Beilstein 10 IV 1611.] |
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