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ChemicalBook--->CAS DataBase List--->358343-63-2

358343-63-2

358343-63-2 Structure

358343-63-2 Structure
IdentificationBack Directory
[Name]

(2E)-3-[4-(benzyloxy)phenyl]-1-(4-ethoxyphenyl)prop-2-en-1-one
[CAS]

358343-63-2
[Synonyms]

hMAO-B-IN-5
(2E)-3-[4-(benzyloxy)phenyl]-1-(4-ethoxyphenyl)prop-2-en-1-one
2-Propen-1-one, 1-(4-ethoxyphenyl)-3-[4-(phenylmethoxy)phenyl]-
[Molecular Formula]

C24H22O3
[MDL Number]

MFCD01901528
[MOL File]

358343-63-2.mol
[Molecular Weight]

358.43
Chemical PropertiesBack Directory
[form ]

Solid
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

hMAO-B-IN-5(B15) is a potent, selective and reversible inhibitor of human monoamine oxidase hMAO-B with IC50 of 0.12 μM. hMAO-B-IN-5 can pass through the blood-brain barrier and can be used in the research of neurodegenerative diseases[1].
[References]

[1] Sachithra Thazhathuveedu Sudevan, et al. Introduction of benzyloxy pharmacophore into aryl/heteroaryl chalcone motifs as a new class of monoamine oxidase B inhibitors. Sci Rep. 2022 Dec 27;12(1):22404. DOI:10.1038/s41598-022-26929-x
Spectrum DetailBack Directory
[Spectrum Detail]

(2E)-3-[4-(benzyloxy)phenyl]-1-(4-ethoxyphenyl)prop-2-en-1-one(358343-63-2)1HNMR
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