Identification | Back Directory | [Name]
15(S)-15-METHYL PROSTAGLANDIN E1 | [CAS]
35700-26-6 | [Synonyms]
15(S)-15-methyl PGE1 OMNFCPCBKCERJP-XBZFKEOQSA-N 15(S)-15-METHYL PROSTAGLANDIN E1 15(S)-15-methyl Prostaglandin E1 9-oxo-11α,15S-dihydroxy-15-methyl-prost-13E-en-1-oic acid 9-OXO-11ALPHA,15S-DIHYDROXY-15-METHYL-PROST-13E-EN-1-OIC ACID Prost-13-en-1-oic acid,11,15-dihydroxy-15-methyl-9-oxo-, (11a,13E,15S)- (9CI) | [Molecular Formula]
C21H36O5 | [MDL Number]
MFCD00135211 | [MOL File]
35700-26-6.mol | [Molecular Weight]
368.51 |
Chemical Properties | Back Directory | [solubility ]
DMF: >100 mg/ml (from PGE1); DMSO: >50 mg/ml (from PGE1); Ethanol: >50 mg/ml (from PGE1); PBS pH 7.2: >1.6 mg/ml (from PGE1) |
Hazard Information | Back Directory | [Description]
15(S)-15-methyl Prostaglandin E1 (15(S)-15-methyl PGE1) is a metabolically stable synthetic analog of PGE1 . In sharp contrast to the bronchodilatory effects of PGE1, 15(S)-15-methyl PGE1 is a weak constrictor of human respiratory tract smooth muscle.1 | [Definition]
ChEBI: 15-Methyl-15S-Prostaglandin E1 is a prostanoid. | [References]
1. Karim, S.M.M., Adaikan, P.G., and Kottegoda, S.R. Prostaglandins and human respiratory tract smooth muscle: Structure activity relationship Adv. Prostaglandin Thromboxane Res. 7,969-980(1980). |
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