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ChemicalBook--->CAS DataBase List--->354583-69-0

354583-69-0

354583-69-0 Structure

354583-69-0 Structure
IdentificationBack Directory
[Name]

1-hexadecyl-2-azelaoyl-sn-glycero-3-phosphocholine
[CAS]

354583-69-0
[Synonyms]

1-hexadecyl-2-azelaoyl-sn-glycero-3-phosphocholine
1-HEXADECYL-2-AZELAOYL-SN-GLYCERO-3-PHOSPHOCHOLINE;AZELAOYL-PAF
[Molecular Formula]

C33H67N2O8P
[MDL Number]

MFCD03412018
[MOL File]

354583-69-0.mol
[Molecular Weight]

650.867
Chemical PropertiesBack Directory
[storage temp. ]

-20°C
[solubility ]

DMF: 33 mg/ml; DMSO: 8 mg/ml; Ethanol: 20 mg/ml; PBS (pH 7.2): 10 mg/ml
[form ]

liquid
Safety DataBack Directory
[Symbol(GHS) ]


GHS06,GHS08
[Signal word ]

Danger
[Hazard statements ]

H302-H315-H319-H331-H336-H351-H361d-H372-H412
[Precautionary statements ]

P201-P273-P301+P312+P330-P302+P352-P304+P340+P311-P308+P313
Hazard InformationBack Directory
[Uses]

Azelaoyl-PAF may be used in binding assay of anti-inflammatory peptides, 2F and 4F.
[Uses]

Azelaoyl-PAF may be used to study its binding affinity with?4F or 2F anti-inflammatory peptides.
[Definition]

ChEBI: 1-O-hexadecyl-2-(8-carboxyoctanoyl)-sn-glycero-3-phosphocholine is a 2-acyl-1-alkyl-sn-glycero-3-phosphocholine in which the alkyl and the acyl groups at positions 1 and 2 are specified as hexadecyl and 8-carboxyoctanoyl respectively. It has a role as a PPARgamma agonist. It is functionally related to a nonanedioic acid. It is a conjugate acid of a 1-O-hexadecyl-2-(8-carboxyoctanoyl)-sn-glycero-3-phosphocholine(1-).
[General Description]

1-hexadecyl-2-azelaoyl-sn-glycero-3-phosphocholine (Azelaoyl-PAF) Azelaoyl-PAF is an alkyl phosphatidylcholine and is a component of the lipid pool within oxidized low-density lipoprotein (oxLDL) particles. Azelaoyl-PAF is a low molecular weight phospholipid.
[Biochem/physiol Actions]

Azelaoyl-PAF (1-hexadecyl-2-azelaoyl-sn-glycero-3-phosphocholine) is a low molecular weight alkyl phosphatidylcholine. It is a constituent of the lipid pool within oxidized low-density lipoprotein (oxLDL) particles. Azelaoyl-PAF serves as a high affinity ligand and agonist for peroxisome proliferator-activated receptor-γ (PPARγ).
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