| Identification | Back Directory | [Name]
H-LYS-THR-GLU-GLU-ILE-SER-GLU-VAL-ASN-STA-VAL-ALA-GLU-PHE-OH | [CAS]
350228-37-4 | [Synonyms]
BACE-IN-1
P10-P4' StatVal
KTEEISEVN-STA-VAEF
KTEETSEVN(STAT)VAEF
B-SECRETASE INHIBITOR
KTEEISEVN [STATINE] VAEF
BETA-SECRETASE INHIBITOR
BETA-SECRETASE INHIBITOR 1
APP BETA-SECRETASE INHIBITOR
KTEEISEVN-Sta-VAEF(Sta=statine)
A4 PROTEIN PRECURSOR770 (662-675)
[ASN670, STA671, VAL672]AMYLOID-BETA
(ASN670,STA671,VAL672)-APP770 (662-675)
AMYLOID PRECURSOR PROTEIN BETA-SECRETASE INHIBITOR
Asn670, Sta671, Val672]-Amyloid β Peptide (662-675)
LYS-THR-GLU-GLU-ILE-SER-GLU-VAL-ASN-STA-VAL-ALA-GLU-PHE
H-LYS-THR-GLU-GLU-ILE-SER-GLU-VAL-ASN-STA-VAL-ALA-GLU-PHE-OH
LYS-THR-GLU-GLU-ILE-SER-GLU-VAL-ASN-[STATINE]-VAL-ALA-GLU-PHE
LYS-THR-GLU-GLU-ILE-SER-GLU-VAL-ASN(STATIN)-VAL-ALA-GLU-PHE-OH
LYS-THR-GLU-GLU-ILE-SER-GLU-VAL-ASN(STATINE)-VAL-ALA-GLU-PHE-OH
(Asn670,Sta671,Val672)-AMyloid b/A4 Protein Precursor770 (662-675)
(Asn670,Sta671,Val672)-Amyloid β/A4 Protein Precursor770 (662-675)
(ASN670,STA671,VAL672)-AMYLOID BETA/A4 PROTEIN PRECURSOR770 (662-675)
L-Phenylalanine, L-lysyl-L-threonyl-L-α-glutamyl-L-α-glutamyl-L-isoleucyl-L-seryl-L-α-glutamyl-L-valyl-L-asparaginyl-(3S,4S)-4-amino-3-hydroxy-6-methylheptanoyl-L-valyl-L-alanyl-L-α-glutamyl-
L-Lysyl-L-threonyl-L-alpha-glutamyl-L-alpha-glutamyl-L-isoleucyl-L-seryl-L-alpha-glutamyl-L-valyl-L-asparaginyl-(3S,4S)-4-amino-3-hydroxy-6-methylheptanoyl-L-valyl-L-alanyl-L-alpha-glutamyl-L-phenylalanine | [Molecular Formula]
C73H118N16O27 | [MDL Number]
MFCD02683580 | [MOL File]
350228-37-4.mol | [Molecular Weight]
1651.81 |
| Chemical Properties | Back Directory | [Boiling point ]
1976.1±65.0 °C(Predicted) | [density ]
1.317±0.06 g/cm3(Predicted) | [storage temp. ]
−20°C | [solubility ]
DMSO: soluble | [form ]
powder | [pka]
3.48±0.10(Predicted) | [color ]
white |
| Hazard Information | Back Directory | [Uses]
β-Secretase inhibitor ([Asn670, Sta671, Val672]-Amyloid β Peptide (662-675)) is a β-secretase and BACE1 inhibitor (IC50: 25 nM for β-secretase)[1]. | [References]
[1] Lin Liu, et al. A colorimetric strategy for assay of protease activity based on gold nanoparticle growth controlled by ascorbic acid and Cu(II)-coordinated peptide. Sensors and Actuators B: Chemical. Volume 266, 1 August 2018, Pages 246-254.
[2] Zhou Y, et al. Tyrosine-Conjugation Method for Evaluating BACE1 Activity Based on Silver Nanoparticles/Metal-Organic Framework Composites as Electrochemical Tags. Chemistry. 2023 May 16;29(28):e202300450. DOI:10.1002/chem.202300450 |
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| Company Name: |
Alabiotech Inc.
|
| Tel: |
001-619-354-5251 |
| Website: |
www.alabiotech-e.com |
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