| Identification | Back Directory | [Name]
7-(diethylamino)-3-(5-methylbenzoxazol-2-yl)-2-benzopyrone | [CAS]
34564-13-1 | [Synonyms]
EMI48
3-(5-Methylbenzoxazole-2-yl)-7-(diethylamino)coumarin
7-(diethylamino)-3-(5-methylbenzoxazol-2-yl)-2-benzopyrone
7-Diethylamino-3-(5-methylbenzoxazol-2-yl)-2H-1-benzopyran-2-one
3-(5-Methylbenzoxazole-2-yl)-7-(diethylamino)-2H-1-benzopyran-2-one
2H-1-Benzopyran-2-one, 7-(diethylamino)-3-(5-methyl-2-benzoxazolyl)- | [EINECS(EC#)]
252-093-4 | [Molecular Formula]
C21H20N2O3 | [MOL File]
34564-13-1.mol | [Molecular Weight]
348.4 |
| Hazard Information | Back Directory | [Uses]
EMI48, the derivative of EMI1, displays greater potency toward mutant EGFR than EMI1. EMI48 inhibits EGFR triple mutants[1]. | [IC 50]
EGFRL858R/T790M/C797S; EGFRdel19 T790M C797S | [storage]
Store at -20°C | [References]
[1] Punit Saraon , et al. A Drug Discovery Platform to Identify Compounds That Inhibit EGFR Triple Mutants.Nat Chem Biol. 2020 May;16(5):577-586. DOI:10.1038/s41589-020-0484-2 |
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R&D Systems, Inc
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18003437475 18003437475 |
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www.rndsystems.com |
| Company Name: |
MedChemExpress
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| Website: |
www.medchemexpress.com |
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