| Identification | Back Directory | [Name]
L-Proline, L-threonyl-L-histidyl-L-arginyl-L-prolyl-L-prolyl-L-methionyl-L-tryptophyl-L-seryl-L-prolyl-L-valyl-L-tryptophyl- | [CAS]
344618-30-0 | [Synonyms]
TfR-T12
L-Proline, L-threonyl-L-histidyl-L-arginyl-L-prolyl-L-prolyl-L-methionyl-L-tryptophyl-L-seryl-L-prolyl-L-valyl-L-tryptophyl- | [Molecular Formula]
C71H99N19O15S | [MDL Number]
MFCD34470446 | [MOL File]
344618-30-0.mol | [Molecular Weight]
1490.73 |
| Hazard Information | Back Directory | [Uses]
TfR-T12 is a BBB-penetrated transferrin receptor (TfR) binding peptide, displaying a binding affinity in the nM range[1][2]. | [References]
[1] Carmen W?ngler, et al. In Vitro and Initial in Vivo Evaluation of (68)Ga-labeled Transferrin Receptor (TfR) Binding Peptides as Potential Carriers for Enhanced Drug Transport Into TfR Expressing Cells. Mol Imaging Biol. 2011 Apr;13(2):332-41. DOI:10.1007/s11307-010-0329-6
[2] Li-Min Mu, et al. Lipid Vesicles Containing Transferrin Receptor Binding Peptide TfR-T 12 and Octa-Arginine Conjugate stearyl-R 8 Efficiently Treat Brain Glioma Along With Glioma Stem Cells. Sci Rep. 2017 Jun 14;7(1):3487. DOI:10.1038/s41598-017-03805-7 |
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