| Identification | Back Directory | [Name]
GinsenosideRo | [CAS]
34367-04-9 | [Synonyms]
PolysciasaponinP3
ChikusetsusaponinV
Chikusetusaponin V
HericiuMsaponin S3
Chikusetsusaponin 5
Ginseng Extract – Ginsenoside
28-(β-D-Glucopyranosyloxy)-28-oxoolean-12-en-3β-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranosiduronic acid
3β-(2-O-β-D-Glucopyranosyl-β-D-glucopyranuronosyloxy)oleana-12-ene-28-oic acid 28-β-D-glucopyranosyl ester
28-(β-D-Glucopyranosyloxy)-28-oxo-5α-olean-12-en-3β-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranosiduronic acid
β-D-Glucopyranosiduronic acid, (3β)-28-(β-D-glucopyranosyloxy)-28-oxoolean-12-en-3-yl2-O-β-D-glucopyranosyl-
β-D-Glucopyranosiduronic acid, (3β)-28-(β-D-glucopyranosyloxy)-28-oxoolean-12-en-3-yl 2-O-β-D-glucopyranosyl- (9CI)
(3beta)-28-(beta-D-Glucopyranosyloxy)-28-oxoolean-12-en-3-yl 2-O-beta-D-glucopyranosyl-beta-D-glucopyranosiduronic acid | [Molecular Formula]
C48H76O19 | [MDL Number]
MFCD01732056 | [MOL File]
34367-04-9.mol | [Molecular Weight]
957.11 |
| Chemical Properties | Back Directory | [Boiling point ]
1018.6±65.0 °C(Predicted) | [density ]
1.14 | [storage temp. ]
Store at 2-8°C, protect from light | [solubility ]
DMSO : 100 mg/mL (104.48 mM; Need ultrasonic) | [form ]
powder | [pka]
2.76±0.70(Predicted) | [color ]
White |
| Hazard Information | Back Directory | [Description]
Ginsenoside Ro is a non-steroid glycoside that has been found in plants of the genus Panax and has anti-inflammatory, antithrombotic, and antiviral biological activities.1,2,3,4,5,6 It inhibits LPS-induced release of reactive oxygen species (ROS) and nitric oxide (NO) as well as inducible nitric oxide synthase (iNOS) and COX-2 protein expression in RAW 264.7 murine macrophages when used at a concentration of 200 μM.2 Ginsenoside Ro dose-dependently inhibits human platelet aggregation induced by thrombin (Item No. 13188) in vitro and thrombin-induced disseminated intravascular coagulation (DIC) in rats when administered at a dose of 100 mg/kg.3,4 It increases the 20-day survival of Sendai virus-infected mice when administered at a dose of 1 mg per day for three days prior to infection.5 Topical administration of ginsenoside Ro (0.2 mg per animal) also stimulates hair regrowth after shaving in a mouse model of slowed hair regrowth.6 | [Definition]
ChEBI: A natural product found in Panax japonicus var. major. |
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