| Identification | Back Directory | [Name]
TM5007 | [CAS]
342595-05-5 | [Synonyms]
TM5007
[2,3'-Bithiophene]-4'-carboxylic acid, 5',5'''-[(1,6-dioxo-1,6-hexanediyl)diimino]bis- | [Molecular Formula]
C24H20N2O6S4 | [MOL File]
342595-05-5.mol | [Molecular Weight]
560.69 |
| Hazard Information | Back Directory | [Uses]
TM5007 is a poent and orally active inhibitor of plasminogen activator inhibitor-1 (PAI-1) with an IC50 of 29 μM. TM5007 enhance fibrinolysis activity and inhibits coagulation. TM5007 also prevents the fibrotic process initiated by bleomycin in mouse lung[1]. | [References]
[1] Izuhara Y, et al. Inhibition of plasminogen activator inhibitor-1: its mechanism and effectiveness on coagulation and fibrosis. Arterioscler Thromb Vasc Biol. 2008 Apr;28(4):672-7. DOI:10.1161/ATVBAHA.107.157479 |
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| Company Name: |
Lynnchem
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86-(0)29-85992781 17792393971 |
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| Company Name: |
Novachemistry
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https://www.novachemistry.com/ |
| Company Name: |
DC Chemicals
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021-58447131 13564518121 |
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