| Identification | Back Directory | [Name]
Catalpol | [CAS]
34168-56-4 | [Synonyms]
Catalponol
Catalpol USP/EP/BP
1(2H)-Naphthalenone,3,4-dihydro-4-hydroxy- 2-(3-methyl-2-butenyl)-,(2R,4S)-
1(2H)-Naphthalenone, 3,4-dihydro-4-hydroxy-2-(3-methyl-2-buten-1-yl)-, (2R,4S)- | [Molecular Formula]
C15H18O2 | [MOL File]
34168-56-4.mol | [Molecular Weight]
230.3 |
| Hazard Information | Back Directory | [Uses]
Catalponol is a naphthoquinone derivative. Catalponol enhances dopamine biosynthesis by inducing tyrosine hydroxylase activity. Catalponol also increases the levels of cAMP and tyrosine hydroxylase phosphorylation in PC12 cells[1][2]. | [References]
[1] Hai-Shan Huang, et al. Catalponol enhances dopamine biosynthesis and protects against L-DOPA-induced cytotoxicity in PC12 cells. J Asian Nat Prod Res. 2009 Oct;11(10):867-75. DOI:10.1080/10286020903193094
[2] Byeong Min Park, et al. Naphthoquinones from Catalpa ovata and their inhibitory effects on the production of nitric oxide. Arch Pharm Res. 2010 Mar;33(3):381-5. DOI:10.1007/s12272-010-0306-2 |
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