| Chemical Properties | Back Directory | [Boiling point ]
581.4±50.0 °C(Predicted) | [density ]
1.68±0.1 g/cm3(Predicted) | [storage temp. ]
Desiccate at RT | [solubility ]
Limited solubility | [pka]
9.06±0.10(Predicted) |
| Hazard Information | Back Directory | [Description]
Brain-specific angiogenesis inhibitor 2 is a protein that in humans is encoded by the BAI2 gene. It is a member of the adhesion-GPCR family of receptors. BAI2 and BAI3 are similar to BAI1 in structure, have similar tissue specificities and may also play a role in angiogenesis. | [Uses]
iMAC2 is a potent MAC inhibitor with an IC50 of 28 nM and an LD50 of 15000 nM. iMAC2 shows anti-apoptotic effect. iMAC2 blocks cytochrome c release[1]. | [storage]
Desiccate at RT | [References]
[1] Peixoto PM, et al. MAC inhibitors suppress mitochondrial apoptosis. Biochem J. 2009 Oct 12;423(3):381-7. DOI:10.1042/BJ20090664 |
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