| Identification | Back Directory | [Name]
(R)-(+)-trans-4-(1-Aminoethyl)-N-(4-pyridyl)cyclohexanecarboxamide Dihydrochloride Monohydrate | [CAS]
331752-47-7 | [Synonyms]
Y-27632 2HCl Monohydrate
Y-27632 Dihydrochloride Hydrate
Y-27632 dihydrochloride monohydrate
Y-27632 monohydrate dihydrochloride
trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinyl-cyclohexanecarboxamide Dihydrochloride Monohydrate
(R)-(+)-trans-4-(1-Aminoethyl)-N-(4-pyridyl)cyclohexanecarboxamide Dihydrochloride Monohydrate
(R)-(+)-trans-4-(1-Aminoethyl)-N-(4-Pyridyl)cyclohexanecarboxamide monohydrate dihydrochloride
Cyclohexanecarboxamide, 4-[(1R)-1-aminoethyl]-N-4-pyridinyl-, dihydrochloride, monohydrate, trans- (9CI) | [Molecular Formula]
C14H25Cl2N3O2 | [MDL Number]
MFCD06245589 | [MOL File]
331752-47-7.mol |
| Chemical Properties | Back Directory | [Appearance]
White Solid | [Melting point ]
180-230°C | [alpha ]
+2～+10°(D/20℃)(c=0.5,CH3OH) | [Boiling point ]
approximate 85℃ | [storage temp. ]
2-8°C | [solubility ]
Acetonitrile (Very Slightly), DMSO (Slightly), Methanol (Slightly), Water (Slightly) | [form ]
Solid | [color ]
White to Off-White | [Water Solubility ]
water: 100mg/mL | [Stability:]
Hygroscopic; Light Sensitive; | [CAS DataBase Reference]
331752-47-7 |
| Hazard Information | Back Directory | [Chemical Properties]
White Solid | [Uses]
A Rho kinase inhibitor (ROCK) for the treatment of ischemia-reperfusion disorders. | [Biological Activity]
Cell permeable: yes''Primary Target
p160 Rho-associated protein kinases (ROCK)''Product competes with ATP.''Reversible: yes''Target Ki: 140 nM for p160 Rho-associated protein kinases (ROCK) |
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