Identification | Back Directory | [Name]
SIRT2 Inhibitor II, AK-1 | [CAS]
330461-64-8 | [Synonyms]
CS-923 AK 1, >=98% AK-1;AK1;AK 1 AK-1 >=98% (HPLC) SIRT2 Inhibitor II, AK-1 Benzamide, 3-[(hexahydro-1H-azepin-1-yl)sulfonyl]-N-(3-nitrophenyl)- 3-(azepane-1-sulfonyl)-N-(3-nitro-phenyl)-benzamide SIRT2 Inhibitor II, AK-1 | [EINECS(EC#)]
604-604-1 | [Molecular Formula]
C19H21N3O5S | [MOL File]
330461-64-8.mol | [Molecular Weight]
403.45 |
Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 10 mg/ml; DMSO: 1 mg/ml; DMSO:PBS (pH 7.2) (1:3): 0.25 mg/ml; Ethanol: 0.3 mg/ml | [form ]
A crystalline solid | [color ]
White to off-white |
Hazard Information | Back Directory | [Description]
AK-1 is a SIRT2 Inhibitor II that prevents hippocampal neurodegeneration in Alzheimer's disease models and induces cell cycle arrest in colon carcinoma cells. | [storage]
Store at -20°C |
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