| Identification | Back Directory | [Name]
3-[(2-METHYL-1,3-THIAZOL-4-YL)ETHYNYL]PYRIDINE | [CAS]
329205-68-7 | [Synonyms]
MTEP
MTEP hydrochloride >=98% (HPLC)
2-methyl-4-(pyridin-3-ylethynyl)thiazole
3-(2-Methyl-thiazol-4-ylethynyl)-pyridine
Pyridine, 3-[(2-methyl-4-thiazolyl)ethynyl]-
3-[(2-METHYL-1,3-THIAZOL-4-YL)ETHYNYL]PYRIDINE
2-methyl-4-(2-pyridin-3-ylethynyl)-1,3-thiazole
3-[2-(2-Methyl-1,3-thiazol-4-yl)ethynyl]pyridine | [Molecular Formula]
C11H8N2S | [MDL Number]
MFCD05260891 | [MOL File]
329205-68-7.mol | [Molecular Weight]
200.26 |
| Chemical Properties | Back Directory | [Boiling point ]
360.7±17.0 °C(Predicted) | [density ]
1.26±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
methanol: 1mg/mL
DMSO: 5mg/mL | [form ]
White to yellow solid. | [pka]
3.41±0.12(Predicted) | [color ]
white to yellow |
| Hazard Information | Back Directory | [Uses]
MTEP Hydrochloride is a potent mGlu5 receptor antagonist, acting as a negative allosteric modulator. | [Biological Activity]
Cell permeable: yes''Primary Target
mGluR5''Product does not compete with ATP.''Reversible: no''Target IC50: 5 nM in Ca2+-flux assay''Target Ki: 16 nM for mGluR5 (metabotropic glutamate receptor subtype-5) |
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