| Identification | Back Directory | [Name]
7-BROMOBENZ[A]ANTHRACENE | [CAS]
32795-84-9 | [Synonyms]
Bromobenzanthracene
7-bromobenzanthracene
7-BROMOBENZ[A]ANTHRACENE
7-bromo-benz(a)anthracen
10-brom-1,2-benzanthracen
10-bromo-1,2-benzanthracene
7-BROMO-BENZ[A]ANTHRACENE 98+%
AR-E 4 7-BROMOBENZ(A)ANTHRACENE
7-Bromobenz[a]anthracene | [Molecular Formula]
C18H11Br | [MDL Number]
MFCD00029016 | [MOL File]
32795-84-9.mol | [Molecular Weight]
307.18 |
| Chemical Properties | Back Directory | [Melting point ]
152 °C | [Boiling point ]
361.79°C (rough estimate) | [density ]
1.3995 (rough estimate) | [refractive index ]
1.6000 (estimate) | [storage temp. ]
Room Temperature, under inert atmosphere | [solubility ]
Chloroform (Slightly), Dichloromethane (Slightly) | [form ]
Solid | [color ]
Light Beige to Dark Yellow | [InChI]
InChI=1S/C18H11Br/c19-18-15-8-4-2-6-13(15)11-17-14-7-3-1-5-12(14)9-10-16(17)18/h1-11H | [InChIKey]
LGRNWCDRODWMOH-UHFFFAOYSA-N | [SMILES]
C12=CC=CC=C1C=CC1C2=CC2C(=CC=CC=2)C=1Br |
| Hazard Information | Back Directory | [Toxicity evaluation]
The tumorigenicity of 7-chlorobenz[α]anthracene (7-C1-BA), an environmental contaminant, and 7-bromobenz[α]anthracene (7-Br-BA) was determined in the male B6C3F1 newborn mouse. Mice receiving 7-C1-BA and 7-Br-BA by i.p. injections at a dose of 1600 nmol per mouse on 1, 8, and 15 days after birth developed 92 and 96% hepatocellular adenomas, and 100 and 83% hepatocellular carcinoma, respectively. Metabolism by liver microsomes of 15-day-old mice each produced the corresponding trans-3,4-dihydrodiol. Analysis by 32P-postlabeling/HPLC indicated the presence of DNA adducts derived from 7-C1-BA trans-3,4-dihydrodiol and 7-Br-BA trans-3,4-dihydrodiol. The results indicate that both 7-C1-BA and 7-Br-BA are potent carcinogens and that bay-region diol epoxides are the ultimate metabolites that lead to DNA adduct formation and tumor initiation[1].
| [References]
[1] Peter P. Fu. “Potent tumorigenicity of 7-chlorobenz[α]anthracene and 7-bromobenz[α]anthracene in the neonatal B6C3F1 male mouse.” Cancer letters 101 1 (1996): Pages 37-42.
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Energy Chemical
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http://www.energy-chemical.com |
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TCI Europe
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320-37350700 |
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| Company Name: |
TCI AMERICA
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800-4238616 |
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