| Identification | Back Directory | [Name]
1-Stearoyl-d35-2-hydroxy-sn-glycero-3-PC | [CAS]
327178-92-7 | [Synonyms]
1-Stearoyl-d35-2-hydroxy-sn-glycero-3-PC | [Molecular Formula]
C26H54NO7P | [MOL File]
327178-92-7.mol | [Molecular Weight]
523.69 |
| Hazard Information | Back Directory | [Biological Activity]
1-Stearoyl-d35-2-hydroxy-sn-glycero-3-PC is intended for use as an internal standard for the quantification of 1-stearoyl-2-hydroxy-sn-glycero-3-PC by GC- or LC-MS. 1-Stearoyl-2-hydroxy-sn-glycero-3-PC is a saturated lysophosphatidylcholine. It increases IL-1β production in isolated human blood monocytes when used at a concentration of 12.5 μM.1 Plasma levels of 1-stearoyl-2-hydroxy-sn-glycero-3-PC are decreased in patients with lung cancer.2 | [References]
1.Liu-Wu, Y., Hurt-Camejo, E., and Wiklund, O.Lysophosphatidylcholine induces the production of IL-1β by human monocytesAtherosclerosis137(2)351-357(1998)
2.Dong, J., Xiaoming, C., Zhao, L., et al.Lysophosphatidylcholine profiling of plasma: Discrimination of isomers and discovery of lung cancer biomarkersMetabolomics6(4)478-488(2010)
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| Company Name: |
Merck KGaA
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(+86) 21 2033 8288 |
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http://www.sigmaaldrich.cn |
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