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ChemicalBook--->CAS DataBase List--->3223-07-2

3223-07-2

3223-07-2 Structure

3223-07-2 Structure
IdentificationBack Directory
[Name]

4-BIS(2-CHLORETHYL)-AMINO-L-PHENYLALANINE HYDROCHLORIDE
[CAS]

3223-07-2
[Synonyms]

EVOMELA
MELPHALAN HCL
MELPHALAN HYDROCHLORIDE
l-sarcolysinehydrochloride
Melphalan hydrochloride CRS
Melphalan for system suitability
phenylalaninemustardhydrochloride
alaninenitrogenmustardhydrochloride
l-phenylalaninemustardhydrochloride
4-BIS(2-CHLORETHYL)-AMINO-L-PHENYLALANINE HYDROCHLORIDE
4-[Bis(2-chloroethyl)amino]-L-phenylalanine hydrochloride
3-(p-(bis(2-chloroethyl)amino)phenyl)-l-alaninhydrochloride
4-(bis(2-chloroethyl)amino)-l-phenylalaninmonohydrochloride
(S)-3-[4-[Bis(2-chloroethyl)amino]phenyl]alanine hydrochloride
4-[Bis(2-chloroethyl)amino]-L-phenylalanine hydrochloride (1:1)
l-3-(p-(bis(2-chloroethyl)amino)phenyl)alaninemonohydrochloride
Phenylalanine, 4-[bis(2-chloroethyl)amino]-, hydrochloride (1:1)
3-(p-(bis(2-chloroethyl)amino)phenyl)-,monohydrochloride,l-alanin
4-BIS(2-CHLORETHYL)-AMINO-L-PHENYLALANINE HYDROCHLORIDE USP/EP/BP
Melphalan Hydrochloride (100 mg) (International Restricted Sales Item)
2-AMINO-3-(4-(BIS(2-CHLOROETHYL)AMINO)PHENYL)PROPANOIC ACID HYDROCHLORIDE (MELPHALAN HYDROCHLORIDE)
[EINECS(EC#)]

643-091-8
[Molecular Formula]

C13H19Cl3N2O2
[MDL Number]

MFCD01674304
[MOL File]

3223-07-2.mol
[Molecular Weight]

341.66
Chemical PropertiesBack Directory
[Melting point ]

175-178 °C
[storage temp. ]

2-8°C
[solubility ]

Aqueous Acid (Slightly), DMSO (Slightly), Methanol (Slightly)
[form ]

Solid
[color ]

White to Off-White
[Stability:]

Moisture Sensitive
Safety DataBack Directory
[Symbol(GHS) ]


GHS08,GHS06
[Signal word ]

Danger
[Hazard statements ]

H330-H361-H340-H350-H310-H300
[Precautionary statements ]

P262-P264-P270-P280-P302+P350-P310-P322-P361-P363-P405-P501-P201-P202-P281-P308+P313-P405-P501-P264-P270-P301+P310-P321-P330-P405-P501-P260-P271-P284-P304+P340-P310-P320-P403+P233-P405-P501
[Toxicity]

TDLo orl-hmn: 1200 mg/kg/5D-I:GIT CCROBU57,369,73
Hazard InformationBack Directory
[Uses]

Melphalan Hydrochloride is used in combined intravitreal chemotherapy with topotecan hydrochloride for viable vitreous seeding from retinoblastoma. Also, it is an anti-cancer chemotherapy drug.
[Safety Profile]

Deadly poison by intravenousroute. Human systemic effects by ingestion: nausea andvomiting. Questionable carcinogen with experimentalcarcinogenic data. When heated to decomposition it emitsvery toxic fumes of Cl-, NOx, and HCl.
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