| Identification | Back Directory | [Name]
3-{[4-(pyridin-2-yl)-1,3-thiazol-2-yl]amino}phenol | [CAS]
315702-75-1 | [Synonyms]
KCC-07
3-[[4-(2-Pyridinyl)-2-thiazolyl]amino]phenol
3-((4-(Pyridin-2-yl)thiazol-2-yl)amino)phenol
3-{[4-(pyridin-2-yl)-1,3-thiazol-2-yl]amino}phenol
KCC07,BAI1,p53,inhibit,ADGRB1,anticancer,Inhibitor,DNA Alkylator/Crosslinker,MBD2,KCC-07,anti-proliferative,ADGR,KCC 07,brain-penetrant | [Molecular Formula]
C14H11N3OS | [MDL Number]
MFCD01121976 | [MOL File]
315702-75-1.mol | [Molecular Weight]
269.32 |
| Chemical Properties | Back Directory | [Boiling point ]
497.7±55.0 °C(Predicted) | [density ]
1.380±0.06 g/cm3(Predicted) | [storage temp. ]
4°C, protect from light | [solubility ]
Soluble in DMSO | [form ]
Solid | [pka]
9.55±0.10(Predicted) | [color ]
White to yellow |
| Hazard Information | Back Directory | [Uses]
KCC 07 is a MBD2 (Methyl-CpG-binding domain protein 2) inhibitor. Prevents binding of MBD2 to methylated DNA and activates brain specific angiogenesis inhibitor 1 (BAI1)/p53 signaling. Inhibits medulloblastoma (MB) cell growth in vitro and reduces tumor size in mice bearing MB xenografts. Brain penetrant. | [storage]
4°C, protect from light |
|
| Company Name: |
DC Chemicals
|
| Tel: |
021-58447131 13564518121 |
| Website: |
http://m.is0513.com/ShowSupplierProductsList927327/0.htm |
| Company Name: |
InvivoChem
|
| Tel: |
13549236410 |
| Website: |
https://www.invivochem.cn/ |
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