| Identification | Back Directory | [Name]
2H-1-Benzopyran-2-one, 6-nitro-3-[2-(phenylamino)-4-thiazolyl]- | [CAS]
313985-59-0 | [Synonyms]
CK2-IN-4
WAY-297674
6-Nitro-3-(2-(phenylamino)thiazol-4-yl)-2H-chromen-2-one
2H-1-Benzopyran-2-one, 6-nitro-3-[2-(phenylamino)-4-thiazolyl]- | [Molecular Formula]
C18H11N3O4S | [MOL File]
313985-59-0.mol | [Molecular Weight]
365.36 |
| Chemical Properties | Back Directory | [Boiling point ]
620.6±65.0 °C(Predicted) | [density ]
1.523±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
2.84±0.10(Predicted) | [color ]
Orange to red |
| Hazard Information | Back Directory | [Uses]
CK2-IN-4 (compound 5) is a protein kinase (CK2) inhibitor (IC50=8.6 μM). CK2-IN-4 has good potential for research in the areas of cancer, viral infections and glomerulonephritis[1]. | [References]
[1] Nakanishi I, et al. Identification of protein kinase CK2 inhibitors using solvent dipole ordering virtual screening. Eur J Med Chem. 2015;96:396-404. DOI:10.1016/j.ejmech.2015.04.032 |
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