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ChemicalBook--->CAS DataBase List--->31373-65-6

31373-65-6

31373-65-6 Structure

31373-65-6 Structure
IdentificationBack Directory
[Name]

HIPPURYL-HIS-LEU
[CAS]

31373-65-6
[Synonyms]

Bz-Gly-His-Leu
HIPPURYL-HIS-LEU
H-HIP-HIS-LEU-OH
BZ-GLY-HIS-LEU-OH
HIPPURYL-HIS-LEU-OH
BENZOYL-GLY-HIS-LEU
HIPPURYL-HISTIDYL-LEUCINE
N-Benzoyl-Gly-L-His-L-Leu-OH
HIPPURYL-L-HISTIDYL-L-LEUCINE
Nα-(Benzoylglycyl)-L-His-L-Leu-OH
Hippuryl-His-Leu-OH |Bz-Gly-His-Leu-OH
N-[N-(N-benzoylglycyl)-L-histidyl]-L-leucine
Hippuryl-L-histidyl-L-leucine, tetrahydrate,99%
Hippuryl-L-histidyl-L-leucine, free base(Synthetic)
[EINECS(EC#)]

250-597-9
[Molecular Formula]

C21H27N5O5
[MDL Number]

MFCD00005205
[MOL File]

31373-65-6.mol
[Molecular Weight]

429.47
Chemical PropertiesBack Directory
[Appearance]

white fine crystalline powder
[Boiling point ]

912.4±65.0 °C(Predicted)
[density ]

1.283±0.06 g/cm3(Predicted)
[storage temp. ]

−20°C
[solubility ]

acetic acid: 50 mg/mL, clear, colorless
[form ]

powder
[pka]

3.26±0.10(Predicted)
[color ]

white to off-white
Hazard InformationBack Directory
[Chemical Properties]

white fine crystalline powder
[Uses]

Hippuryl-His-Leu-OH is a substrate for detecting the activity of angiotensin I converting enzyme. The His-Leu released by Hippuryl-His-Leu-OH can react with o-phtbaldialdehyde or Fluorescamine (HY-D0715) for fluorescence detection[1][2][3].
[References]

[1] Nishimura K, et al. Purification of angiotensin I-converting enzyme from human lung. Biochim Biophys Acta. 1977 Aug 11;483(2):398-408. DOI:10.1016/0005-2744(77)90067-5
[2] Santos RA, et al. An improved fluorometric assay of rat serum and plasma converting enzyme. Hypertension. 1985 Mar-Apr;7(2):244-52. DOI:10.1161/01.hyp.7.2.244
[3] Horiuchi M, et al. Method for determination of angiotensin-converting enzyme activity in blood and tissue by high-performance liquid chromatography. J Chromatogr. 1982 Dec 10;233:123-30. DOI:10.1016/s0378-4347(00)81738-7
Safety DataBack Directory
[WGK Germany ]

3
[F ]

10-21
Spectrum DetailBack Directory
[Spectrum Detail]

HIPPURYL-HIS-LEU(31373-65-6)MS
HIPPURYL-HIS-LEU(31373-65-6)IR1
HIPPURYL-HIS-LEU(31373-65-6)IR2
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