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ChemicalBook--->CAS DataBase List--->31255-10-4

31255-10-4

31255-10-4 Structure

31255-10-4 Structure
IdentificationBack Directory
[Name]

Ethane, 1,2-bis(2-bromoethoxy)-
[CAS]

31255-10-4
[Synonyms]

31255-10-4
CAS_31255-10-4
Br-PEG2-bromide
Bromo-PEG3-bromide
Bromo-PEG2-bromide
1,2-Bis(2-bromoethoxy)ethane
Ethane, 1,2-bis(2-bromoethoxy)-
[Molecular Formula]

C6H12Br2O2
[MDL Number]

MFCD00466590
[MOL File]

31255-10-4.mol
[Molecular Weight]

275.97
Chemical PropertiesBack Directory
[Boiling point ]

140 °C(Press: 12 Torr)
[density ]

1.6777 g/cm3
[storage temp. ]

-20°C Freezer, Under inert atmosphere
[solubility ]

Chloroform, Ethyl Acetate (Slightly)
[form ]

Oil
[color ]

Colourless
[Stability:]

Moisture Sensitive
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P280-P301+P312-P302+P352-P305+P351+P338
Hazard InformationBack Directory
[Description]

Bromo-PEG2-bromide is a PEG linker containing two bromide groups. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media.
[Uses]

Bromo-PEG2-bromide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
[IC 50]

PEGs
[References]

[1] Chen TH, et al. Metal-organic frameworks constructed from crown ether-based 1,4-benzenedicarboxylic acid derivatives. Dalton Trans. 2016 Feb 21;45(7):3063-9. DOI:10.1039/c5dt04316f
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