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ChemicalBook--->CAS DataBase List--->30465-68-0

30465-68-0

30465-68-0 Structure

30465-68-0 Structure
IdentificationBack Directory
[Name]

5-METHOXYQUINOLIN-8-AMINE
[CAS]

30465-68-0
[Synonyms]

5-METHOXYQUINOLIN-8-AMINE
5-methoxy-8-quinolinamine
8-AMINO-5-METHOXYQUINOLINE
5-methoxy-8-aminoquinoline
8-QuinolinaMine, 5-Methoxy-
5-METHOXY-QUINOLIN-8-YLAMINE
8-Amino-5-methoxyquinoline 95%
[Molecular Formula]

C10H10N2O
[MDL Number]

MFCD01593679
[MOL File]

30465-68-0.mol
[Molecular Weight]

174.2
Chemical PropertiesBack Directory
[Melting point ]

90-95°C
[Boiling point ]

355.7±27.0 °C(Predicted)
[density ]

1.217±0.06 g/cm3(Predicted)
[storage temp. ]

Keep in dark place,Inert atmosphere,2-8°C
[form ]

powder
[pka]

3.98±0.12(Predicted)
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H335
[Precautionary statements ]

P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard InformationBack Directory
[Uses]

The Chen auxiliary was reported to be an effective directing group in the synthesis of pyrrolidones from assisting in the activation of C(sp3)-H bonds and can be readily installed through amide bond formation and removed through mild conditions using CAN at room temperature.
[General Description]

8-Amino-5-methoxyquinoline is a substituted quinoline derivative that can be prepared using 5-chloro-2-nitroaniline as a starting material. It can act as an easily removable directing group and also mediate C-H activation. These properties have been useful for synthesizing isomeric dibenzoxazepinones and complex pyrrolidinones from compounds containing 8-amino-5-methoxyquinoline moiety.
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