Identification | Back Directory | [Name]
5-METHOXYQUINOLIN-8-AMINE | [CAS]
30465-68-0 | [Synonyms]
5-METHOXYQUINOLIN-8-AMINE 5-methoxy-8-quinolinamine 8-AMINO-5-METHOXYQUINOLINE 5-methoxy-8-aminoquinoline 8-QuinolinaMine, 5-Methoxy- 5-METHOXY-QUINOLIN-8-YLAMINE 8-Amino-5-methoxyquinoline 95% | [Molecular Formula]
C10H10N2O | [MDL Number]
MFCD01593679 | [MOL File]
30465-68-0.mol | [Molecular Weight]
174.2 |
Chemical Properties | Back Directory | [Melting point ]
90-95°C | [Boiling point ]
355.7±27.0 °C(Predicted) | [density ]
1.217±0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Inert atmosphere,2-8°C | [form ]
powder | [pka]
3.98±0.12(Predicted) |
Hazard Information | Back Directory | [Uses]
The Chen auxiliary was reported to be an effective directing group in the synthesis of pyrrolidones from assisting in the activation of C(sp3)-H bonds and can be readily installed through amide bond formation and removed through mild conditions using CAN at room temperature. | [General Description]
8-Amino-5-methoxyquinoline is a substituted quinoline derivative that can be prepared using 5-chloro-2-nitroaniline as a starting material. It can act as an easily removable directing group and also mediate C-H activation. These properties have been useful for synthesizing isomeric dibenzoxazepinones and complex pyrrolidinones from compounds containing 8-amino-5-methoxyquinoline moiety. |
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