Identification | Back Directory | [Name]
BOC-8-AMINOCAPRYLIC ACID | [CAS]
30100-16-4 | [Synonyms]
BOC-8-AOC-OH BOC-AOC(8)-OH BOC-NH-(CH2)7-COOH RARECHEM EM WB 0025 BOC-AMINOCAPRYLIC ACID Boc-8-aminooctanoicaci BOC-8-AMINOCAPRYLIC ACID BOC-8-AMINOOCTANOIC ACID 8-(BOC-AMINO)CAPRYLIC ACID 8-(BOC-AMINO)OCTANOIC ACID N-Boc-8-amino-octanoic acid (Tert-Butoxy)Carbonyl 8-Aoc-OH BOC-8-AMINOCAPRYLIC ACID USP/EP/BP Boc-8-aminocaprylic acid≥ 97% (HPLC) T-BUTOXYCARBONYL-8-AMINOCAPRYLIC ACID T-BUTOXYCARBONYL-8-AMINOOCTANOIC ACID N-T-BUTYLOXYCARBONYL-8-AMINO-OCTANOIC ACID N-TERT-BUTYLOXYCARBONYL-8-AMINO-OCTANOIC ACID Boc-8-aminooctanoic acid (Boc-aminocaprylic acid) 8-[[(1,1-dimethylethoxy)carbonyl]amino]Octanoic acid Octanoicacid, 8-[[(1,1-dimethylethoxy)carbonyl]amino]- 8-(Boc-amino)caprylic acid, 8-(Boc-amino)octanoic acid | [Molecular Formula]
C13H25NO4 | [MDL Number]
MFCD00270350 | [MOL File]
30100-16-4.mol | [Molecular Weight]
259.34 |
Chemical Properties | Back Directory | [Melting point ]
56-59 °C
| [Boiling point ]
406.0±28.0 °C(Predicted) | [density ]
1.036±0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [pka]
4.78±0.10(Predicted) | [BRN ]
2268966 |
Hazard Information | Back Directory | [Description]
Boc-8-aoc-oh can be used as a PROTAC linker in the synthesis of PROTACs. Boc-8-aoc-oh is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine. | [Chemical Properties]
White amorphous powder | [Uses]
Reagent to introduce a protected w-amino alkyl spacer. Longer spacer arms often impart increased activity to the substrate |
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