| Identification | Back Directory | [Name]
N-Cyclohexyl-6-[[N-(2-methoxyethyl)-N-methylamino]methyl]-N-methylthiazolo[3,2-a]benzoimidazole-2-carboxamidesesquifumarate | [CAS]
299900-84-8 | [Synonyms]
YM-202074 sesquifumarate salt hydrate
N-cyclohexyl-6-{[(2-methoxyethyl)(methyl)amino]methyl}-N-methylthiazolo[3,2-a]benzimidazole-2-carboxamide
N-cyclohexyl-7-[[2-methoxyethyl(methyl)amino]methyl]-N-methyl-[1,3]thiazolo[3,2-a]benzimidazole-2-carboxamide
N-Cyclohexyl-6-[[N-(2-methoxyethyl)-N-methylamino]methyl]-N-methylthiazolo[3,2-a]benzoimidazole-2-carboxamidesesquifumarate | [Molecular Formula]
C26H34N4O6S | [MDL Number]
MFCD16879020 | [MOL File]
299900-84-8.mol | [Molecular Weight]
530.64 |
| Hazard Information | Back Directory | [Uses]
YM 202074 is a highly selective mGluR-1 antagonist. | [Biological Activity]
YM-202074 is a potent and selective allosteric metabotropic glutamate receptor type 1 (mGluR1) antagonist. It bound an allosteric site of r at mGluR1 with a Ki value of 4.8 nM. It also inhibited the mGluR1-mediated inositol phosphates production in r at cerebellar granule cells with an IC50 value of 8.6 nMwhile showing selectivity over mGluR(2-7). |
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| Company Name: |
Energy Chemical
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| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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