| Hazard Information | Back Directory | [Description]
13C6 Glucosylsphingosine (d18:1) is an isotopically enriched form of 1-β-D-glucosylsphingosine (d18:1) that is intended for use as an internal standard for the quantification of 1-β-D-glucosylsphingosine by GC- or LC-MS. 1-β-D-Glucosylsphingosine is a lysolipid derivative of glucosylcerebroside that decreases activity of glucocerebrosidase in LA-N-2 cells in a dose-dependent manner.1,2
| [storage]
Store at -20°C | [References]
1. Murugesan, V., Chuang, W.-L., Liu, J., et al. Glucosylsphingosine is a key biomarker of Gaucher disease Am. J. Hematol. 91(11),1082-1089(2016).
2. Schueler, U.H., Kolter, T., Kaneski, C.R., et al. Toxicity of glucosylsphingosine (glucopsychosine) to cultured neuronal cells: A model system for assessing neuronal damage in Gaucher disease type 2 and 3 Neurobiol. Dis. 14(3),595-601(2003). |
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