| Identification | Back Directory | [Name]
P-fluorobenzenesulfonic acid p-fluorobenzenesulfonic acid methyl | [CAS]
2905-15-9 | [Synonyms]
Tubulin inhibitor 29
Bicalutamide Impurity 36
Bicalutamide Impurtiy 23
S-(4-fluorophenyl) 4-fluorobenzenesulfonothioate
Benzenesulfonothioic acid, 4-fluoro-, S-(4-fluorophenyl) ester
P-fluorobenzenesulfonic acid p-fluorobenzenesulfonic acid methyl | [Molecular Formula]
C12H8F2O2S2 | [MOL File]
2905-15-9.mol | [Molecular Weight]
286.32 |
| Hazard Information | Back Directory | [Uses]
Tubulin inhibitor 29 (compound 3c) is a potent tubulin inhibitor with an IC50 value of 1.2 μM. Tubulin inhibitor 29 shows antiproliferative effects with an IC50 value of 7.5 μM for MCF-7 cells. Tubulin inhibitor 29 inhibits tubulin assembly and bounds in the colchicine site[1]. | [References]
[1] Khodyuk RGD, et al. Diaryl disulfides and thiosulfonates as combretastatin A-4 analogues: Synthesis, cytotoxicity and antitubulin activity. Bioorg Chem. 2020 Aug;101:104017. DOI:10.1016/j.bioorg.2020.104017 |
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