PD-L1-IN-2 (compound 11c) (i.p.; 25/50 mg/kg; once a day; 16 days) decreases the tumor sizes with an inhibition rate of 45% at 45 mg/kg, and the average tumor weight of the 50 mg/kg groups is significantly lower than that of the PBS group[1].
| Animal Model: | C57BL/6 mice with subcutaneous MC38 tumors[1] |
| Dosage: | 25/50 mg/kg |
| Administration: | i.p.; 25/50 mg/kg; once a day; 16 days |
| Result: | Suppressed MC38 tumor growth in vivo. |